Reparto principal
Keanu Reeves
Duke Caboom (voice)
Laurence Fishburne
Morpheus
Carrie-Anne Moss
Trinity
Hugo Weaving
Agent Smith
Jada Pinkett Smith
Maureen Evans
Gloria Foster
Oracle
Harold Perrineau
Link
Monica Bellucci
Persephone
Harry Lennix
Commander Lock
Lambert Wilson
The Merovingian
Randall Duk Kim
Keymaker
Nona Gaye
Zee
Anthony Zerbe
Councillor Hamann
Daniel Bernhardt
Henchman (uncredited)
Helmut Bakaitis
The Architect
David Kilde
Agent Jackson
Matt McColm
Guard (uncredited)
鄒兆龍
Seraph
Neil Rayment
Twin #1
Adrian Rayment
Twin #2